![]() VALVULATED INHALATION CHAMBER
专利摘要:
tube inhalation chamber a tube inhalation chamber includes a main chamber housing and a mouthpiece assembly removably coupled to a first end of the main chamber housing, the mouthpiece assembly including a mouthpiece housing having the mouthpiece and a part of the valve housing, a retaining ring provided on the inside and coupled to the part of the valve housing, and a one-way inhalation valve having an annular valve seat member, wherein the valve seat member valve is maintained between the retaining ring and a coupling surface of the valve housing part. in a particular embodiment, a portion of the first end of the main chamber housing engages the bottom of the valve seat member and creates a seal between the main chamber housing and a one-way inhalation valve and between the air inhalation valve a track and the housing of the mouthpiece. 公开号:BR112013006254B1 申请号:R112013006254-1 申请日:2011-09-14 公开日:2021-03-30 发明作者:Dirk Ernest Von Hollen;Ashwin Kumar Viswanath 申请人:Koninklijke Philips N.V.; IPC主号:
专利说明:
The present invention pertains to systems for the application of respiratory medications, and in particular to a valve inhalation chamber having a valve retention system. DESCRIPTION OF THE PREVIOUS TECHNIQUE Is it well known to apply medications to a patient's respiratory system for the treatment of a - disease using equipment for the application of respiratory medications. For example, a patient suffering from an acute asthmatic attack can use equipment for the application of respiratory medications for the application of a bronchodilator, such as albuterol (salbutamol), in the form of a fine mist to the patient's respiratory system. Conventional equipment for the application of respiratory medications usually consists of a metered dose inhaler ("MDI") and a spacer or valve holding chamber. The MDI, also known simply as an "inhaler", includes a container or nebulizer containing 20 pressure medication and a container support, also called a boot, which is typically shaped like an "L". If the patient uses the container support as a mouthpiece to receive the aerosolized medication in his airways directly from the aerosol dispensing the container support leg, this configuration may not optimize the mixture of the medication with the air, because the aerosolized medication is directly injected into the airways. Without the proper mixing of the drug with the air, the medication may not be inhaled into the patient's lungs where it becomes effective, but may form droplets that are deposited in the patient's mouth and swallowed without the medicinal effect. wanted. In order to improve the mixing of the medication with the air, it is known to provide a spacer, also commonly referred to as a valve retention chamber, which attaches to the aerosol application end (the outlet end) of the container support. The spacer, which is typically a small hollow cylinder with a one-way valve at the downstream end, receives the aerosol from the container and allows it to form a fine mist for inhalation into the patient's airways. Optionally, a mask can be provided at the end of the spacer opposite the MDI, so that the patient can breathe through the mouth to receive the medication. Examples of conventional valve retention chambers and associated components are shown in U.S. Patents No. 4,470,412; 4,809,692; and 4,832,015 all by Nowacki et al .; U.S. Patent No. 15 5,012,803 to Foley et al. ; U.S. Patent No. 5,042,467 to Foley; U.S. Patent No. 5,385,140 to Smith, U.S. Patent No. 5,848,599 to Foley et al. , and U.S. Patent No. 6,557,549 to Schmidt et al. Although the valve retention chambers 20 described in these patents improve the mixing of the medication with the air, further improvements in the design of the equipment for the application of respiratory medications are still desirable. In one embodiment, the valve inhalation chamber includes a main chamber housing and a mouthpiece assembly removably coupled to a first end of the main chamber housing, the mouthpiece assembly including a mouthpiece housing having the mouthpiece and a part of the valve housing, a retaining ring provided inside and coupled to the part of the valve housing, and a one-way inhalation valve having an annular valve seat member, wherein the seat member valve is maintained between the retaining ring and a mating surface of the valve housing part. In a particular embodiment, a portion of the first end of the main chamber housing engages the bottom of the valve seat member and creates a seal between the main chamber housing and the one-way inhalation valve and between the inhalation valve of a track and the housing of the mouthpiece. These and other objectives, details and characteristics of the present invention, as well as the methods of operation and the functions of the related elements of structure and combination of parts and manufacturing economies, will become more apparent after considering the following description and the appended claims. with reference to the accompanying drawings, all forming part of the present specification, in which equal reference numerals indicate corresponding parts in the various figures. However, it must be expressly understood that the drawings are for the purpose of illustration and description only, and are not intended to be a limitation on the limits of the invention. As used in the specification and the claims, the singular form of "one", "one", and "a / o" includes the referring plurals, unless the context clearly indicates otherwise. FIGURES 1, 2, 3 and 4 are front, bottom, rear and exploded isometric views, respectively, of the valve inhalation chamber according to an exemplary embodiment of the present invention; FIGURES 5, 6, 7 and 8 are front isometric, rear isometric, front elevation and rear elevation views, respectively, of a housing of the mouthpiece that forms part of the valve inhalation chamber of FIGURES 1, 2, 3 and 4; FIGURES 9, 10, and 11 are isometric front views, isometric rear views and rear elevation views, respectively, of a duckbill valve that forms part of the valve inhalation chamber of FIGURES 1, 2, 3 and 4; FIGURES 12, 13, and 14 are isometric front views 5, in lateral elevation, and in frontal elevation, respectively, of a retaining ring that forms part of the valve inhalation chamber of FIGURES 1, 2, 3 and 4; FIGURES 15-18 illustrate how the mouthpiece assembly of the valve inhalation chamber of FIGURES 1, 2, 3 and 4 10 is assembled in accordance with an exemplary embodiment of the present invention; and FIGURE 19 is a cross-sectional diagram showing the main chamber housing connected to the mouthpiece part housing in the valve inhalation chamber 15 of FIGURES 1, 2, 3 and 4. The directional phrases used in the present, for example, and without limitations, top, bottom, left, right, up, down, front, rear and their derivatives, refer to the orientation of the elements shown in the drawings and are not limiting of the claims, unless expressly mentioned herein. As used herein, the statement that two or more parts or components are "coupled" means that the parts are joined or operate together, either directly or through one or more intermediate parts or components. As used herein, the statement that two or more parts or components are "joined" together means that the parts exert a force against each other, 30 either directly or through one or more intermediate parts or components. As used herein, the term "number" means one or an integer greater than one (that is, a plurality). FIGURES 1, 2, 3 and 4 are front, bottom, rear and exploded isometric views, respectively, of the valve inhalation chamber 2 according to 5 with an exemplary embodiment of the present invention. The valve inhalation chamber 2 is structured to be used in connection with a metered dose inhaler (not shown) having a container inserted in a boot piece as previously described herein. The valve inhalation chamber 2 includes 10 generally a cylindrical housing of the main chamber 4, which can be made of, for example, and without limitation, an antistatic plastic material. In addition, the mouthpiece assembly 6, described in greater detail earlier in the present, is coupled to the front end 8 of the housing 15 of the main chamber 4. The lid 10 is attached to the bottom of the mouthpiece assembly 6, being structured to selectively attach to the mouthpiece assembly 6 when a tube 2 inhalation chamber is not being used. The valve inhalation chamber 2 further includes the two-piece MDI adapter 12 which is structured to be removably attached to the second end 14 of the main chamber housing 4. The MDI adapter 12 is structured to receive and retain the MDI. The MDI adapter 12 includes a rigid end cap 16 made of, for example, a hard plastic or any other suitable rigid material that is structured to be selectively attached to the rear end of the main chamber 14. The MDI adapter 12 also includes a portion flexible inner 18 made of a flexible material such as, without limitation, silicone, rubber, 30 TPE or foam, among other suitable materials. The internal part 18 is structured to be received and fixed by the end cap 16 and can be made to be removable, so that it can be cleaned and / or replaced in case of damage, or, alternatively, it can be permanently fixed to the end cap 16 by a process such as overmoulding. The flexible inner part 18 includes walls that define a structured opening to the boot piece 12 of an MDI. The flexible nature of the inner part 18 enables it to fix MDIs of different shapes and sizes. In addition, the end cap 16 has an air-actuated noisemaker device 20 included, which in the illustrated embodiment is in the form of a whistle. The noisemaker 20 in the shown embodiment is a high airflow indicator structured to generate noise when the air flowing through the main chamber housing 4 as a result of the patient's inhalation exceeds a predetermined level. Thus, the noisemaker 20 provides the patient with a previous indication that he is inhaling very quickly and that he must reduce the breathing rate. As seen in FIGURES 1 and 4, the exhalation valve element 22 is operationally coupled to the mouthpiece assembly 6, being structured to allow the exhaled gases 20 to escape from the valve inhalation chamber 2. In the illustrated embodiment, the valve element exhalation valve 22 is in the form of a flapped exhalation valve, being positioned at the top of the mouthpiece assembly 6 in a plane parallel or almost parallel to the longitudinal axis of the main chamber housing 4. In the exemplary and non-exclusive realization, the exhalation valve element 22 is positioned at the top of the mouthpiece assembly 6 in a plane that is at a five-degree angle to a plane that is parallel to the longitudinal axis of the main chamber housing 4. This orientation maximizes the visibility of the exhalation valve element 22 by the patient while the valve inhalation chamber 2 is being used, so that the patient can monitor whether it is exhaling with the appropriate strength, at the right time and / or for the appropriate duration. The mouthpiece assembly 6 includes three components, the mouthpiece part housing 24, a 5-way inhalation valve in the form of duckbill elastomeric valve 26 and retaining ring 28, each of which is further described in detail below . FIGURES 5, 6, 7 and 8 are isometric front, isometric rear, front elevation and 10 rear elevation views, respectively, of the nozzle part 24 housing. The nozzle part 24 housing includes a part of the valve housing 30 coupled to the part of the mouthpiece 32 structured to be received by the patient's lips when using the valve inhalation chamber 2. In the exemplary embodiment, the housing of the mouthpiece 24 is made of an antistatic plastic material. The exhalation valve seat 34 for retaining and securing the exhalation valve element 20 is provided at the top of the valve housing part 30 and includes holes 36 and 38 (ie 20 exhalation ports) and slot 40 through of which the exhalation valve element 20 is inserted. The interior of the valve housing part 30 includes frames 42 and coupling surface 44, the purposes of which are described hereinabove. In addition, as seen in FIGURES 5, 7 and 8, the interior 25 of the mouthpiece part 32 includes the vertical bar 46, which acts as a restraining element preventing the person from inserting their fingers into the mouthpiece assembly 6 through the the mouthpiece part 32. Finally, the valve housing part 30 includes slots 48 which are structured to receive teeth 50 on the outside of the main chamber housing 4 to connect the main chamber housing 4 and mouthpiece assembly 6 to each other . FIGURES 9, 10, and 11 are isometric front views, isometric rear views and rear elevation views, respectively, of the duckbill valve 26. In the exemplary embodiment, the duckbill valve 26 is made of an elastomeric material such as silicone rubber. The duck nozzle valve 5 includes a valve seat member 52 having holes 54A, 54B, 54C provided therein. The duckbill valve 26 also includes lips 56A, 56B extending upwardly from valve seat member 52. FIGURES 12, 13, and 14 are front isometric views 10, in side elevation, and in front elevation, respectively, of the retaining ring 28. In the exemplary embodiment, the retaining ring 28 is made of an antistatic plastic material. The retaining ring 28 generally includes an annular bottom wall 58 having an external annular wall 15 which extends thereafter. An extension member 62 extends outwardly from the outer wall 60. In addition, guide beacons 64A, 64B, 64C are provided on the bottom wall 58 and extend from there upwards. FIGURES 15-18 illustrate how the mouthpiece assembly 20 is assembled in accordance with an exemplary embodiment of the present invention. With reference to FIGURES 15 and 16, the duckbill valve 26 is first coupled to the retaining ring 28 by inserting the guide beacons 64A, 64B, 64C into the respective holes 54A, 54B, 54C, so that the seat member 25 of the valve 52 is located inside the outer wall -60 and rests on the bottom wall 58. With reference to FIGURES 17 and 18, the coupled duckbill valve 26 and the retaining ring 28 are inserted in the valve housing part 30 of the nozzle part housing 24. In particular, 30 each extension member 62 is inserted into a respective frame 42, where, for example, a friction fit or by some other means is retained as a suitable adhesive. As seen in FIGURE 18, the valve seat member 52 is held between the bottom wall 58 of the retaining ring 28 and the coupling surface 44 of the valve housing part 30. With reference to FIGURE 19, when the mouthpiece assembly 6 is assembled as described, the main chamber housing 5 can be connected to the mouthpiece assembly 6 by inserting teeth 50 into the slots 48. As seen in FIGURES 4 and 19, the front end 8 of the main chamber housing 4 includes a tapered tapered edge 66. When the main chamber housing 4 is connected to the mouthpiece assembly 6 as described, the tapered edge 66 engages the bottom of the valve seat member 52 (which also has a conical tapered shape), compressing it and pushing it firmly against the coupling surface 44, thus producing a seal. Then, the remaining components 15 of the valve inhalation chamber can be assembled as shown in FIGURES 1-4 and previously described. Although the invention has been described in detail for the purpose of illustration based on what is currently considered to be the most practical and preferred embodiments, it should be understood that these details serve only the purpose and that the invention is not limited to disclosures presented, but, on the contrary, intends to cover modifications and equivalent arrangements that are within the spirit and scope of the appended claims 25. For example, it should be understood that the present invention contemplates that, as far as possible, one or more characteristics of an embodiment can be combined with one or more characteristics of any other embodiment.
权利要求:
Claims (12) [0001] 1. VALVULATED INHALATION CHAMBER (2), comprising: a main chamber housing (4); and a mouthpiece assembly (6) removably coupled to a first end of the main chamber housing, the mouthpiece assembly including a mouthpiece housing (24) having a portion of the mouthpiece (32) and a portion of the valve housing (30), a retaining ring (28) provided inside and coupled to the valve housing part, and a one-way inhalation valve (26) having an annular valve seat member (52), in that the valve seat member is held between the retaining ring and a coupling surface of the valve housing part, where the one-way inhalation valve and the retaining ring are structured to be inserted and kept inside the part of the valve housing, characterized by the valve seat member (52) including a bottom that engages a bottom wall (58) of the retaining ring (28), wherein a part of the first end of the main chamber housing (4) attaches to the bottom of the ass member then valve and creates a seal between the main chamber housing and the one-way inhalation valve (26) and between the one-way inhalation valve and the mouthpiece housing (24). [0002] 2. VALVE INHALATION CHAMBER, according to claim 1, characterized in that the one-way inhalation valve is a duckbill elastomeric valve. [0003] 3. VALVULATED INHALATION CHAMBER, according to claim 1, characterized in that the retaining ring and the coupling surface are structured to exert a compressive force on the valve seat member when the mouthpiece assembly is not coupled to the main chamber housing. [0004] 4. VALVULATED INHALATION CHAMBER, according to claim 1, characterized in that the part of the first end of the main chamber housing is a tapered edge (66), and in which the bottom of the valve seat member is tapered. [0005] VALVE INHALATION CHAMBER according to claim 1, characterized in that the retaining ring includes a generally annular bottom wall (58) and a generally annular outer wall (60), in which the valve seat member is housed within the outer wall and includes a bottom that attaches to the bottom wall. [0006] VALVE INHALATION CHAMBER according to claim 5, characterized in that the valve seat member includes a plurality of holes (54A, 54B, 54C), wherein the bottom wall includes a plurality of guide beacons (64A, 64B , 64C), and in which each guide beacon is received through one of the respective holes. [0007] 7. VALVE INHALATION CHAMBER according to claim 5, characterized in that the part of the valve housing includes a plurality of frame members (42), wherein the outer wall includes a plurality of extension members (62), and in that each of the extension members is received within one of the respective frame members. [0008] 8. VALVE INHALATION CHAMBER, according to claim 1, characterized in that the part of the mouthpiece includes an internal restraining element (46) that restricts access to the interior of the mouthpiece assembly through the part of the mouthpiece. [0009] 9. VALVULATED INHALATION CHAMBER, according to claim 1, characterized in that the internal restraining element is a bar that extends from a first side of the inside of the mouthpiece part to a second side of the inside of the mouthpiece part . [0010] 10. VALVULATED INHALATION CHAMBER, according to claim 1, characterized in that the mouthpiece housing is made of an antistatic plastic material. [0011] 11. VALVULATED INHALATION CHAMBER, according to claim 10, characterized in that the retaining ring is made of an antistatic plastic material. [0012] 12. VALVE INHALATION CHAMBER, according to claim 1, characterized in that the mouthpiece housing includes an exhalation port (36, 38) provided in one of its 10 upper parts and a flap valve for exhalation (22) operationally coupled to the exhalation port, where the exhalation flap valve is structured to be positioned in a user's line of sight when part of the mouthpiece is inserted into the user's mouth.
类似技术:
公开号 | 公开日 | 专利标题 BR112013006254B1|2021-03-30|VALVULATED INHALATION CHAMBER JP3618775B2|2005-02-09|Mask with spout valve ES2343239T3|2010-07-27|DPI TYPE INHALER. ES2389908T3|2012-11-02|Enhanced Spacer ES2224548T3|2005-03-01|NEBULIZATION CHAMBER FOR INHALER-DOSER. US6718969B1|2004-04-13|Medication dosage inhaler system US8141551B2|2012-03-27|Mouthpiece and flow rate controller for intrapulmonary delivery devices JP5608677B2|2014-10-15|Holding chamber and mask with valve ES2402241T3|2013-04-30|Modular Spray Supply System PT2015813E|2011-02-01|Improvement of a dry powder inhaler US20090062855A1|2009-03-05|Baby nebulizer US20120318261A1|2012-12-20|Valved Holding Chamber With Whistle for the Administration of Inhalable Drugs US6990976B2|2006-01-31|Asthma drug inhaler with whistle BR112012016540B1|2020-03-24|RESPIRATORY MEDICINE ADMINISTRATION AND FEEDBACK DEVICE AND COMPLIANCE FOR USE WITH A MEDICINE STORAGE AND ADMINISTRATION DEVICE BR9913924A|2001-06-19|Inhaler for inhalation drug delivery, plurality of inhalers, and container adapted for use in an inhaler US20080083409A1|2008-04-10|Inhaler US20170119986A1|2017-05-04|Face Mask for Inhalation, Suitable for Delivering a Therapeutic Gas or Molecule As part of A Treatment By Inhalation, In Particular In Children ES2344667T3|2010-09-02|ONE-WAY DIAPHRAGM VALVE FOR AEROSOL INHALATION SYSTEM FOR AEROSOL PULMONARY ADMINISTRATION. BR112012013003B1|2020-04-22|nozzle for an apparatus to assist in administering aerosol to a patient, and apparatus for administering pharmaceutical aerosol to a patient EP1747791B1|2012-07-25|Asthma preparation inhaler auxiliary device with reed US20200197654A1|2020-06-25|Nasal mask with aromatic dispenser PT721359E|2000-11-30|FACE MASK US20190366018A1|2019-12-05|Valved Spacer for Inhalation Device CN110831647B|2022-02-01|Spacer for atomizer US20080190420A1|2008-08-14|Aerosol Medication Delivery Apparatus
同族专利:
公开号 | 公开日 WO2012038861A1|2012-03-29| US9364621B2|2016-06-14| CN103096959A|2013-05-08| JP2013537080A|2013-09-30| BR112013006254A2|2020-06-09| EP2618876A1|2013-07-31| EP2618876B1|2018-11-14| CN103096959B|2016-02-03| JP5919277B2|2016-05-18| US20130186393A1|2013-07-25|
引用文献:
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法律状态:
2020-06-23| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]| 2020-07-21| B25D| Requested change of name of applicant approved|Owner name: KONINKLIJKE PHILIPS N.V. (NL) | 2020-07-28| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]| 2020-08-11| B25G| Requested change of headquarter approved|Owner name: KONINKLIJKE PHILIPS N.V. (NL) | 2021-01-19| B09A| Decision: intention to grant| 2021-03-30| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/09/2011, OBSERVADAS AS CONDICOES LEGAIS. |
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申请号 | 申请日 | 专利标题 US38474110P| true| 2010-09-21|2010-09-21| US61/384,741|2010-09-21| PCT/IB2011/054020|WO2012038861A1|2010-09-21|2011-09-14|Valved holding chamber including valve retention system| 相关专利
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